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Structure of Cysteine-free Human Insulin-Degrading Enzyme in complex with Substrate-selective Macrocyclic Inhibitor 37

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Structure of Cysteine-free Human Insulin-Degrading Enzyme in complex with Substrate-selective Macrocyclic Inhibitor 37 Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ALA-ALA-ALA, Insulin-degrading enzyme, ... Authors: Tan, G.A, Seeliger, M.A, Maianti, J.P, Liu, D.R. Deposit date: 2017-12-21 Release date: 2019-04-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.95624845742 Å) Cite: Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme. Nat.Chem.Biol., 15, 2019
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2017-12-21
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