Correlation between tumor immunohistochemical (IHC) stains and germline mutations in 28 suspected Lynch Syndrome patients.

$, Tumor IHC sensitivity for germline defects.
†, LOVD, London open variation database (V2.0 build 35) maintained by International Society of Gastroenterological Hereditary Tumors (InSiGHT). Variants were classified according to Consensus InSiGHT Classification v.1.9: 5/09/2013.
‡, HGMD, human gene mutation database. Dis causing, disease causative mutation; Our data were checked against this database as of 10 Jan 2014.
Novel mutations were highlighted in bold; VUS, variant of uncertain significance; NA, not applicable.