Vitamin A and its derivative retinol are essential for the development of intestinal adaptive immunity. Retinoic acid-producing myeloid cells are central to this process, but how myeloid cells acquire

NIAID Data Ecosystem60

Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity. Selective IL-27 production by intestinal regulatory T cells permits gut-specific regulation of Th17 immunity

肠道免疫调节

Treg细胞亚群

Regulatory T cells (Treg cells) are instrumental in establishing immunological tolerance. However, the precise effector mechanisms by which Treg cells control a specific type of immune response in a g

NIAID Data Ecosystem40

IL22_transcriptomics_in_intestinal_epithelial_cells

肠道免疫调节

抗感染防御机制

The Interleukin-22 (IL22) pathway plays a key role in maintaining homeostasis at the mucosal surfaces and is frequently dysregulated during infectious and inflammatory diseases. The IL-22 cytokine is

NIAID Data Ecosystem100

Single cell analysis of ROR-gamma-t-expressing immune cells in the mesenteric lymph nodes of healthy mice

RORγt+免疫细胞图谱

肠道免疫调节

The focus of this study is to define the full spectrum of ROR-gamma-t-expressing immune cells in the mouse mesenteric lymph nodes of healthy mice. Results from this study may yield novel findings on t

NIAID Data Ecosystem50

Effect of LcS on LI-LPMC in <i>Tcra</i><sup><i>-/-</i></sup> mice during rWAS exposure.

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