Foxa2

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity; double-stranded DNA binding; INVOLVED IN positive regulation of transcription by RNA polymerase II; regulation of DNA-templated transcription; response to insulin; PARTICIPATES IN forkhead class A signaling pathway; Hedgehog signaling pathway; maturity-onset diabetes of the young pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; Diaphragmatic Hernia (ortholog); Experimental Liver Cirrhosis (ortholog); FOUND IN nucleus; cell junction (ortholog); nucleoplasm (ortholog); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17beta-estradiol

编码一种表现出DNA结合转录激活剂活性、RNA聚合酶II特异性；DNA结合转录因子活性；双链DNA结合；参与RNA聚合酶II介导的转录正调控；DNA模板转录调控；胰岛素反应；参与forkhead类A型信号通路；Hedgehog信号通路；青年型糖尿病途径；与实验性糖尿病；膈肌裂孔（同源）；实验性肝硬变（同源）相关；存在于细胞核；细胞连接（同源）；核质（同源）；与1,2-二甲基肼；1-萘基异硫氰酸酯；17β-雌二醇相互作用。