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Study of the ability of TXT-compounds to promote telomeric G4 DNA thermal stabilization using FRET melting assay

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DataCite Commons2023-03-24 更新2025-04-16 收录
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The data set contains a DNA melting screen obtained from the FRET melting assay. Thermal stabilities of G-quadruplex structures were analysed in the presence and in absence of ligands. TMPyP4 and MTX were used as references. Measurements were carried out in triplicate using a LightCycler 480 thermocycler (Roche Life Science) with a filter setting of 465 nm/510 nm at 30–95°C with a rate of 0.01°C/s.

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2023-03-20
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