Response of mammary tissue to high-LET HZE particle (Silicon ions) radiation or low-LET gamma-rays

Transcriptional profiling of mammary tissue irradiated at 10 weeks of age with either 100 cGy sparsely ionizing gamma-rays or 10 cGy or 30 cGy densely ionizing radiation (350 MeV/amu Si). Mammary tissue was collected 1 weeks 4 weeks and 12 weeks post-irradiation. Four radiation treatment groups: sham 100 cGy sparsely ionizing gamma-rays 10 cGy or 30 cGy densely ionizing radiation (350 MeV/amu Si). Three time points post-irradiation (1 4 and 12 weeks). Three or four replicates per time point.

对10周龄乳腺组织进行100 cGy稀疏电离伽马射线照射或10 cGy或30 cGy密集电离辐射（350 MeV/amu Si）的转录组分析。照射后第1周、第4周和第12周收集乳腺组织。分为四组辐射处理：假照射组、100 cGy稀疏电离伽马射线照射组、10 cGy或30 cGy密集电离辐射（350 MeV/amu Si）组。照射后分别于第1周、第4周和第12周进行三次时间点观察。每个时间点设有三或四个重复样本。