The GATA4 gene is transcribed to yield mRNA and the mRNA is translated to yield GATA4 protein (inferred from mouse homologs). MESP1 binds the promoter of the GATA4 gene and activates transcription (in
Background Angiotensin II (AII), has been suggested to promote muscle loss. Reducing AII synthesis, by inhibiting angiotensin converting enzyme (ACE) activity has been proposed as a method to inhibit
GATA4 is an essential transcription factor required for the development and function of multiple tissues, including a major role in gonadogenesis. Despite its crucial role, the molecular mechanisms th
