Design and synthesis of thiophene dihydroisoquinolins as novel BACE-1 inhibitors
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Design and synthesis of thiophene dihydroisoquinolins as novel BACE-1 inhibitors Descriptor: BETA-SECRETASE 1, N-(6-chloro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)-3-[2-propyl-4-(1H-pyrazol-4-yl)thiophen-3-yl]-L-alanine, ZINC ION Authors: Lougheed, J.C, Brecht, E, Yao, N.H. Deposit date: 2012-11-20 Release date: 2013-03-06 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
创建时间：
2012-11-20
