Short-term intensive fasting rejuvenates erythropoiesis
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE200918
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How erythropoiesis responds to fasting remains to be explored. Here, Xu et al. showed that short-term intensive fasting promotes the production of red blood cells and boosts their functions by regulating MS4A3-CDK2 module to enhance megakaryocyte-erythroid progenitor self-renewal and erythroid-biased differentiation. We sorted megakaryocyte–erythroid progenitor cell from the BM of 6h fasted mice and control mice for bulk RNA-seq to investigate the molecular influence which fasting poses on erythropoiesis.
创建时间：
2023-01-02
