CRC_scRNAseq

Data matrix and metafiles for CRC scRNAseq.rds.gz: A total of 54,103 cell transcriptomes from 5 colorectal cancer patients of which 29,481 cells originated from tumors and 24,622 cells from adjacent non-malignant tissues. The file is the Seurat object list which includes the expression matrix and annotation of 58 cell types. CellRanger_Output: Sequenced reads were then mapped to GRCh38 whole genome using 10X Genomics' Cell Ranger 3 software's cell ranger count function. This compressed file includes Cell Ranger output of filtered_feature_bc_matrix for each sample.

结直肠癌（Colorectal Cancer, CRC）单细胞RNA测序（single-cell RNA sequencing）数据集CRC scRNAseq.rds.gz的表达矩阵与元数据文件：共包含来自5名结直肠癌患者的54103个细胞转录组，其中29481个细胞来源于肿瘤组织，其余24622个细胞来源于癌旁非恶性组织。该文件为Seurat对象列表，涵盖58种细胞类型的表达矩阵与注释信息。
CellRanger_Output：测序读数通过10X Genomics公司的Cell Ranger 3软件的cell ranger count功能比对至人类参考基因组GRCh38。该压缩文件包含所有样本的过滤后的特征-条形码矩阵（filtered_feature_bc_matrix）的Cell Ranger输出结果。

搜集汇总

背景与挑战

背景概述

CRC_scRNAseq是一个结直肠癌单细胞RNA测序数据集，包含来自5名患者的54,103个细胞转录组，涵盖肿瘤和邻近非恶性组织，并提供了58种细胞类型的注释。该数据集以Seurat对象和Cell Ranger输出格式提供，适用于癌症研究和细胞亚型分析，由上海交通大学医学院发布，采用CC BY 4.0开放许可证。