RNA-sequencing reveals the modulation of the NLRP3 inflammasome by miR-223-3p in extracellular vesicles in bacterial endophthalmitis

Extracellular Vesicles (EVs) are critical mediators of cell-cell communication via transfer of molecular cargo including miRNAs and regulate transcription in various physiological and pathological conditions. This study aimed to investigate the role of extracellular vesicle (EV)-derived-microRNAs (EV-miRNAs) in bacterial endophthalmitis, focusing on their regulatory impact on inflammation and host immune responses.