HePulse 885534J3

HePulse 885534J3 Dataset - A New Design of Precision Silver Doped Diamond-Like Carbon Coating with Superior Bio-Mechanical Performance: Silver (Ag) doped diamond-like carbon (DLC) coatings are in high demand for biomedical applications. However, excess Ag doping in typical Ag/DLC coatings reduces mechanical performance and poses cytotoxicity to human cells. In this work a new Ag/DLC coating model is proposed with precise doping of Ag in a DLC matrix in the form of isolated nanoparticles embedded at controlled depths. The new version of Ag/DLC is designed to perform robust antimicrobial action in the early post-surgery stages, while a confined Ag amount maintains the excellent mechanical and biocompatibility performance of the underlying DLC coating when compared to typical Ag/DLC designs. Pure DLC without Ag, typically made Ag/DLC having 17 at. % Ag doped throughout the DLC matrix and new Ag/DLC coatings with 2 at. % precise Ag doping, are made with a modified magnetron sputtering system with control over the deposition process. The coatings are characterised for structural, mechanical, ion leaching, and cytotoxicity profiles against L929 fibroblast cells. The typical and new Ag/DLC coatings have similar ion release rates of ~ 0.6 ppm and the new design outperforms the typical Ag/DLC with 63% higher hardness, 100% higher Young’s modulus, and 21% higher biocompatibility. This enhanced biomechanical performance of the proposed new Ag/DLC design could have significant potential for coating of load-carrying medical devices.

HePulse 885534J3 数据集 - 一种新型高精度银掺杂金刚石碳膜涂层设计与优异生物力学性能：银掺杂金刚石碳（Ag/DLC）涂层因生物医学应用需求而备受青睐。然而，在典型的 Ag/DLC 涂层中，银掺杂量过多会降低其机械性能，并对人体细胞产生细胞毒性。本研究提出了一种新的 Ag/DLC 涂层模型，其中在 DLC 矩阵中以孤立的纳米颗粒形式，在可控深度精确掺杂银。该新型 Ag/DLC 涂层设计旨在在术后早期阶段发挥强大的抗菌作用，同时，通过限制银的量，维持底层 DLC 涂层的卓越机械性能和生物相容性，相较于典型的 Ag/DLC 设计，表现出更优的性能。纯 DLC（不含银）以及通常的 Ag/DLC（在整个 DLC 矩阵中掺杂 17 at. % 的银）和新型的 Ag/DLC（精确掺杂 2 at. % 的银）均采用改进的磁控溅射系统制造，该系统对沉积过程有严格的控制。涂层在结构、机械性能、离子浸出和针对 L929 纤维母细胞系的细胞毒性方面进行了表征。典型和新型 Ag/DLC 涂层具有相似的离子释放速率（约为 0.6 ppm），而新的设计在硬度方面表现出 63% 的提升，杨氏模量方面提升了 100%，生物相容性方面提高了 21%。所提出的新的 Ag/DLC 设计在生物力学性能方面的提升，对于承重医疗设备的涂层具有巨大的潜在应用价值。