Parameter estimates from segregation analysis of ovarian cancer in 1919 proband-ascertained pedigrees.

†Parameters in square brackets were fixed at the values indicated; ‡M indicates Mendelian transmission: τAA = 1.0, τAB = 0.5, τBB = 0.0.§The meaning of γ parameters is as follows: γmd represents mother/daughter residual association; γss represents sister/sister residual association; *Parameter hit bound; §No. of independent parameters: (no. of parameters in model) – (no. of parameters fixed at boundary) – (no. of dependent and or fixed parameters); Chi-square is defined as (-2 ln L) of the data under the specific hypothesis minus (−2 ln L) of the data under the general model.