Introduction: Immunotherapy is the first-line treatment for intermediate-advanced stage hepatocellular carcinoma (HCC), although its outcomes vary. This study aimed to identify imaging biomarkers of i

DataCite Commons2024-11-17 更新50

Association between HPK1 expression and T-cell exhaustion. Association between HPK1 expression and T-cell exhaustion

肿瘤免疫学

T细胞耗竭

We aimed to investigate the association between HPK1 expression and exhausted status of tumor. Overall design: Bulk RNA-seq was performed on fresh-frozen tissue samples of renal cell carcinoma.

NIAID Data Ecosystem60

Transcriptome analysis of tumor infiltrating NK and T cells in CT26-bearing BALB/C mice

肿瘤免疫学

肿瘤浸润淋巴细胞

CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie

NIAID Data Ecosystem60

Moderate-intensity aerobic exercise training improves CD8+ tumor-infiltrating lymphocytes effector function by reducing mitochondrial loss

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