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Long-read RNA-Seq analysis of the full-length F8 transcript in iPSCs

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE229621
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We repaired the variant in iPSCs derived from a patient with moderate hemophilia A. To confirm the restoration of the full-length F8 transcript in the gene-corrected iPSCs, we performed long-read RNA-Seq analysis in iPSCs with the EF1α promoter. Full-length F8 transcript in healthy donor-derived iPSCs or variant-corrected or uncorrected patient-derived iPSCs
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2023-12-14
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