Self-cleaving guide RNAs enable pharmacological selection of precise gene editing events in vivo
收藏NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE216550
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In this study we compared the gene expression of mice that had received the rAAV-GR-Cypor scgRNA and rAAV-spCas9 with and without APAP selection. APAP selected mice were also compared to mice which had received the rAAV-GR-Hpd miRNA. Livers from terminally harvested mice were isolated and RNA was extracted using RNAzol. Gene expressions profiles and expression of integrated rAAV constructs were compared between the different groups.
创建时间：
2023-01-03
