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Human sterol 14a-demethylase (CYP51) in complex with the substrate lanosterol

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Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6uez
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Human sterol 14a-demethylase (CYP51) in complex with the substrate lanosterol Descriptor: LANOSTEROL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE Authors: Hargrove, T.Y, Wawrzak, Z, Lepesheva, G.I. Deposit date: 2019-09-23 Release date: 2020-06-10 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.98 Å) Cite: A requirement for an active proton delivery network supports a compound I-mediated C-C bond cleavage in CYP51 catalysis. J.Biol.Chem., 295, 2020
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2019-09-23
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