Crystal structure of pregnane X receptor ligand binding domain complexed with T0901317 analog T0-BP
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Crystal structure of pregnane X receptor ligand binding domain complexed with T0901317 analog T0-BP Descriptor: N-[([1,1'-biphenyl]-4-yl)methyl]-N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide, Nuclear receptor subfamily 1 group I member 2 Authors: Huber, A.D, Poudel, S, Seetharaman, J, Miller, D.J, Lin, W, Li, Y, Chen, T. Deposit date: 2023-01-04 Release date: 2023-03-15 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-guided approach to modulate small molecule binding to a promiscuous ligand-activated protein. Proc.Natl.Acad.Sci.USA, 120, 2023
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2023-01-04
