X-ray crystal structure of compound 17r bound to human Chk1 kinase domain
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X-ray crystal structure of compound 17r bound to human Chk1 kinase domain Descriptor: GLYCEROL, N-(3-methylisothiazol-5-yl)-3-(1-methyl-1H-pyrazol-4-yl)-5-[(3R)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine, Serine/threonine-protein kinase Chk1 Authors: Fischmann, T.O. Deposit date: 2010-09-10 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.6455 Å) Cite: Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach-Part 1. Bioorg.Med.Chem.Lett., 21, 2011
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2010-09-10
