X-ray crystal structure of compound 2a bound to human CHK1 kinase domain
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X-ray crystal structure of compound 2a bound to human CHK1 kinase domain Descriptor: 2-(4-chlorophenyl)-4-[(3S)-piperidin-3-ylamino]thieno[3,2-c]pyridine-7-carboxamide, GLYCEROL, Serine/threonine-protein kinase Chk1 Authors: Fischmann, T.O. Deposit date: 2010-10-18 Release date: 2010-12-08 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.59 Å) Cite: Design, synthesis and SAR of thienopyridines as potent CHK1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
创建时间:
2010-10-18



