Cytokine Expression in the Mouse Brain in Response to Immune Activation by Corynebacterium parvum
收藏PubMed Central2026-05-16 收录
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Cytokine expression in the brain has been suggested to mediate various sickness behaviors. Here we report that intraperitoneal injection of a Corynebacterium parvum antigen in C57BL/6 mice was followed by prolonged upregulation of cytokines in the cerebral cortex and subcortical structures in a time course that coincided with reduced spontaneous running activity.
