Anti-HIV activity (EC50) of labyrinthopeptin A1 (LabyA1) against laboratory-adapted and drug-resistant HIV strains determined in various cell types.
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aViral replication measured by MTS/PES method. Mean ± SEM out of 2–6 independent experiments is shown.bViral replication measured by p24 HIV-1 or p27 HIV-2 Ag ELISA. Mean ± SEM out of 2–8 independent PBMC donor experiments is shown.cHIV-1 strains resistant to the anti-carbohydrate mAb 2G12, CXCR4 antagonist AMD3100, gp41 fusion inhibitor enfuvirtide (T20), RTI azidothymidine (AZT), INI raltegravir (RAL) and the CD4/gp120 binding inhibitor feglymycin (FGM).
创建时间:
2015-12-02



