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Chip-Seq analysis of HAUSP and HIF-1alpha

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE76770
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We reported that HAUSP (USP7) deubiquitinase interacts with and deubiquitinates HIF-1α to increase its stability and functions. HAUSP, HIF-1alpha and CBP could form a complex to regulate histone modification and gene transcription To identify the overlapping set of genes bound by HAUSP and HIF-1alpha, (1) H1299 and MDA-MB 231 cells were used for Chip-seq analysis of HAUSP, (2) H1299 cells lysate was used for Chip-seq analys of HIF-1alpha, and (3) H1299 cell as an input
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2019-06-26
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