Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZJ12
收藏Protein Data Bank Japan2023-11-29 更新2026-03-28 收录
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Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor ZJ12 Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(3-ethyl-6-methoxy-1,2-benzoxazol-5-yl)-2-methoxy-benzenesulfonamide Authors: Zhang, M, Wang, C, Zhang, C, Zhang, Y, Xu, Y. Deposit date: 2021-08-06 Release date: 2022-08-10 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.82 Å) Cite: Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia. Acta Pharmacol.Sin., 43, 2022
创建时间：
2021-08-06
