Molecular and pathological subtypes related to prostate cancer disparities and disease outcomes in African American and European American patients

To investigate genetic and molecular differences that may exist between prostate cancers of African American and European American origin. Gene expression profile analysis was performed comparing RNA seq data of African American prostate cancer cell lines (inhouse) and European American prostate cancer cell lines (public repository) Overall design: Comparative gene expression profiling analysis of RNA-seq data for African American cell lines (RC77T, RC43T, and RC165T [inhouse], and MDA Pca 2b [public repository]) and European American cell lines (LNCaP, VCaP, and RWPE-2) Please note that the MDA PCa2b, LNCaP, VCaP, and RWPE-2 data sets are already available to the public: SRR8615579: MDA PCa 2b, LNCaP, and VCaP SRR10575173: RWPE-2