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Inactivation of the nuclear interacting SET domain protein 1 (NSD1) impairs GATA1-regulated erythroid differentiation and causes erythroleukemia. NSD1 Add-back experiment, mRNASeq cultured erythroblasts.. Inactivation of the nuclear interacting SET domain protein 1 (NSD1) impairs GATA1-regulated erythroid differentiation and causes erythroleukemia. NSD1 Add-back experiment, mRNASeq cultured erythroblasts.

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下载链接:
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA563709
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资源简介:
In vitro differentiation of Nsd1-/- erythroblasts with retroviral expression of wildtype Nsd1, or a catalytically-inactive Nsd1N1918Q SET-domain Overall design: Add-back experiment with cultured Nsd1-/- erythroblasts rescued with either retroviral expression of wildtype Nsd1, or a catalytically-inactive Nsd1N1918Q SET-domain
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2019-09-03
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