Additional file 2: Table S2. of Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s disease

A table to assess whether the various demographic and neuro-pathological variables may be confounding the relationship between miRNA expression and pathological AD. A linear model is used to model miRNA expression by Study, Age at death, Sex, neuronal proportion (NNLS), post-mortem interval (PMI), RNA Integrity number (RIN) and pathological AD. The effect of pathological AD on the miRNA is reported (coef.AD) as well as the probability of observing this effect or something more extreme assuming that it should be zero (pval.AD). Then for each of the covariates a model is fit without including this covariate in the model and the effect of AD on miRNA expression is calculated again; e.g. pval.AD (−Age) is from the model not including Age at death. (CSV 28 kb)