The X-ray structure of Human Prostasin in complex with a covalent benzoxazole inhibitor
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The X-ray structure of Human Prostasin in complex with a covalent benzoxazole inhibitor Descriptor: GLYCEROL, Prostasin, benzyl [(1R)-1-({(2S,4R)-2-({(1S)-5-amino-1-[(S)-1,3-benzoxazol-2-yl(hydroxy)methyl]pentyl}carbamoyl)-4-[(4-methylbenzyl)oxy]pyrrolidin-1-yl}carbonyl)-3-phenylpropyl]carbamate Authors: Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. Deposit date: 2008-07-31 Release date: 2008-09-09 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2008-07-31
