Effect of oat beta-glucan on intestinal injury in mice with food allergy

Food allergy (FA) can lead to intestinal inflammation and tissue damage, allowing antigens easier access into the bloodstream and triggering more severe allergic symptoms. Oat beta-glucan (OBG), a linear polysaccharide primarily found in oat bran, has been demonstrated to possess immunomodulatory properties and regulate gut microbiota. This study aimed to investigate the impact of OBG on FA-induced colonic damage and allergic symptoms, and to explore its potential mechanism.