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In-depth proteomic analysis of secretome and whole cells of mouse astrocyte
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2014-12-31
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Cell and sub-compartment specific proteomics reveals astrocyte contributions in a mouse model of OCD. Cell and sub-compartment specific proteomics reveals astrocyte contributions in a mouse model of OCD
We investigated the sub-proteomes of different functional compartments in astrocyte and neurons in the striatum. We compared the proteomes to the cell-specific RNA profiles of neurons and astrocytes f
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Chronic Sleep Deprivation-Induced Proteome Changes in Astrocytes of the Rat Hypothalamus
Sleep deprivation (SD) can influence cognition, memory, and sleep/wake homeostasis and can cause impairments in many physiological processes. Because the homeostatic control of the sleep/wake cycle is
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Mouse Prefontal Cortex Astrocyte Proteome
Anxiety disorders are among the most common and disabling mental health disorders worldwide with inadequate therapeutic options. Numerous clinical and research studies indicate essential neuronal cont
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Monitoring Astrocytic Proteome Dynamics by Cell Type-Specific Protein Labeling
The ability of the nervous system to undergo long-term plasticity is based on changes in cellular and synaptic proteomes. While many studies have explored dynamic alterations in neuronal proteomes dur
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Immunogold electron microscopy showing the localization of CGB and SgII in secretory granule-like vesicles (large dense-core vesicles) in astrocytes of brain tissues.
Astrocytes from human brain tissues were immunolabeled for CGB (A) and SgII (B) (15 nm gold) with the affinity purified CGB and SgII antibodies, respectively. The CGB- or SgII-labeling gold particles
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