Data for: Novel meriolin derivatives as rapid apoptosis inducers

NIAID Data Ecosystem2026-03-11 收录

药物化合物

抗癌药物发现

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Supporting Information of preparative details, characterization, and NMR spectra

创建时间：

2019-06-25

Mannolides A–C with an Intact Diterpenoid Skeleton Providing Insights on the Biosynthesis of Antitumor Cephalotaxus Troponoids

天然产物化学

抗癌药物发现

Three new diterpenoids, mannolides A–C (1–3), and two new Cephalotaxus troponoids, 4 and 5, were isolated from Cephalotaxus mannii and structurally characterized by spectroscopic data and X-ray crysta

NIAID Data Ecosystem40

Manuscript data.pdf

抗癌药物发现

计算机辅助药物设计

These data are tables of the in silico study part in the manuscript "In-vitro Cytotoxicity and In-silico Insights of the Multi-target Anticancer Candidates from Haplophyllum tuberculatum".

Figshare2020-08-16 更新00

Discovery of Cell-Permeable Macrocyclic Cyclin A/B RxL Inhibitors that Demonstrate Antitumor Activity

抗癌药物发现

蛋白相互作用抑制剂

The cyclin-dependent kinase (CDK)/retinoblastoma protein (RB)/early region 2 binding factor (E2F) axis forms the core transcriptional machinery driving cell cycle progression. Alterations in RB1 or ot

Figshare2025-08-14 更新00

Design, Synthesis, and Bioactivity Evaluation of Dual-Target Inhibitors of Tubulin and Src Kinase Guided by Crystal Structure

微管蛋白/Src双靶点抑制剂

抗癌药物发现

Klisyri (KX01) is a dual tubulin/Src protein inhibitor that has shown potential therapeutic effects in several tumor models. However, a phase II clinical trial in patients with bone-metastatic castrat

NIAID Data Ecosystem40

S1 Data -

抗癌药物发现

分子对接

Cancer stands as a significant global cause of mortality, predominantly arising from the dysregulation of key enzymes and DNA. One strategic avenue in developing new anticancer agents involves targeti

NIAID Data Ecosystem00

Data for: Novel meriolin derivatives as rapid apoptosis inducers

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