NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [ChIP]

ChEBI2011-11-29 更新2026-07-21 收录

表观遗传调控

癌症分子机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-29146 数据链接链接失效反馈

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NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [ChIP]

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2011-11-29

Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation

组蛋白修饰与肿瘤发生

表观遗传调控

In this study, our results support a functional divergence between H3K36me2 and H3K36me3 and their non-redundant roles in H3K36M-driven oncogenesis Overall design: 17 ChIP-seq samples, 3 RNA-seq sampl

NIAID Data Ecosystem50

Table_1_ABCC6 Knockdown Fuels Cell Proliferation by Regulating PPARα in Hepatocellular Carcinoma.xls

癌症分子机制

ABCC6基因功能

The ATP binding cassette (ABC) transporter family is ubiquitous in eukaryotes, specifically in vertebrates, and plays a crucial role in energy homeostasis, cell signaling, and drug resistance. Accumul

NIAID Data Ecosystem20

Transcriptional Dynamics of Skeletal Muscle in Obesity (PRJCA023478)

肥胖相关转录组学

表观遗传调控

Skeletal muscle is a metabolically active organ, but it remains largely unexplored in obesity. Here, we used diet-induced mice as obesity model to investigate the effect of obesity on muscle transcrip

NIAID Data Ecosystem00

DataSheet4_PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer.zip

癌症分子机制

细胞周期调控

The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. The relevant biological functions of PRR11 in pan-cancer development are not well understood. In the current study,

NIAID Data Ecosystem30

Epigenetic basis for monocyte dysfunction in acute-on-chronic liver failure and alcoholic hepatitis [RNA-seq]

肝病相关单核细胞功能障碍

表观遗传调控

BACKGROUND/ AIMS: Severe forms of alcoholic liver disease are associated with increased susceptibility to infections largely due to immune dysfunction. In this study, we analyze the phenotypic, molecu

NIAID Data Ecosystem10

NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [ChIP]

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