PROBLEM TO BE SOLVED: To provide a method for manufacturing a chemical treatment material capable of obtaining a desired performance while reducing an amount of impregnation of a chemical agent. SOLUT
A methodology is presented that allows hazardous dipolar aprotic solvents used in the pharmaceutical processing industries to be replaced with solvent-pair mixtures that consist of a hydrogen-bond don
A design of experiments (DoE) approach was taken to optimize purity and reaction yield of the final debenzylation and hydrochloride salt formation of IPI-926. The study involved a careful dissection o
