Reprogramming to pluripotency through a somatic stem cell intermediate
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Reprogramming to pluripotency through a somatic stem cell intermediate
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2014-03-28
相关数据集
Expression profiling of skin fibroblast and iPSC from Werner Syndrome
The premature aging disorder Werner Syndrome (WS) is characterized by early onset of aging phenotypes resembling natural aging. In most WS patients there are mutations in the DNA helicase WRN, an enzy
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RBBP4 is an epigenetic barrier for inducing pluripotent stem cells to totipotent 2C-like cells [scRNA-seq]. RBBP4 is an epigenetic barrier for inducing pluripotent stem cells to totipotent 2C-like cells [scRNA-seq]
Cellular totipotency is critical for generating a whole organism, yet how to establish totipotency is still poorly illustrated. Unlike pluripotent stem cells, abundant transposable elements (TEs) are
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MOESM1 of Derivation of induced pluripotent stem cells from orangutan skin fibroblasts
Additional file 1. Log-transformed gene expression scores from orangutan fibroblasts and iPSCs. A complete list of log-transformed gene expression scores from orangutan fibroblasts and iPSCs is provid
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The trophectoderm acts as a niche for the inner cell mass through IL-6 signaling [reprogramming_embryo]. The trophectoderm acts as a niche for the inner cell mass through IL-6 signaling [reprogramming_embryo]
IL-6 has been shown to be required for somatic cell reprogramming into induced pluripotent stem cells (iPSCs). However, how the cytokine is regulated and if it plays a role during embryo development r
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High-efficiency cellular reprogramming with microfluidics. Homo sapiens
We report that the efficiency of reprogramming human somatic cells to induced pluripotent stem cells (hiPSCs) can be dramatically improved in a microfluidic environment. Microliter-volume confinement
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