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Multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in picolitre-sized droplets [large_scale_drug_screen]

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174695
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K562 cells were perturbed with drug combinations for 12h in droplets. Subsequently cells were processed to generate libraries for RNA-Seq. Large scale drug screen was performed, in which 3x 420 combinatorial treatment conditions were generated and analysed by RNA-Seq (large_scale_matrix). For each replicate one additional control was performed called DMSO_DMSO_ctrl.
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2021-05-20
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