Additional file 3 of The autophagy interaction network of the aging model Podospora anserina

Yeast two-hybrid analysis. The results of the yeast two-hybrid analysis including the accession ID, the number of clones, the trivial names, and the putative function. For each prey clone of the non-singletons the position of the first amino acid is given in a separate sheet. In addition, the file contains each edge and node of the hybrid network, which was deduced from the interactions of the yeast two-hybrid analysis and the corresponding homologous proteins from yeast and human (see Additional file 10: Figure S1). Two edge types can be distinguished. First, edges indicating an interaction, where the source and the target node correspond to proteins in the same species. Second, edges indicating a homologous relation, where the source protein belongs to P. anserina and the target protein to yeast or human. UniProt accession numbers were used as identifiers for proteins of yeast and human. The identifiers for P. anserina proteins were adopted from the P. anserina genome database [10]. Species were distinguished by their NCBI taxonomy IDs: Homo sapiens (9606), Podospora anserina (5145) and Saccharomyces cerevisiae S288c (559292). (XLS 88 kb)