GWAS Summary Statistics from "Sex and statin-related genetic associations at the PCSK9 gene locus – results of genome-wide association meta-analysis"

GWAMA summary statistics of PCSK9 levels stratified by sex and statin useage in Europeans.

When using this data, please cite:

Pott, J., Kheirkhah, A., Gadin, J.R. et al. Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis. Biol Sex Differ 15, 26 (2024). https://doi.org/10.1186/s13293-024-00602-6

All txt files contain the following columns:

markername (unique SNP ID)

chr

bp_hg19 (base position according to hg19)

EA (effect allele)

OA (other allele)

EAF (effect allele frequency)

info (minimal info score across all used studies)

nSamples (sample size per SNP)

nStudies (in case of double-stratified data: number of studies; in case of single-stratified data: 2, as it is a meta-analysis of the two double-stratified data sets)

beta (effect estimate)

SE (standard error)

pval (p-value)

I2 (SNP heterogeneity across studies)

invalidAssoc (TRUE/FALSE flag if this variant was excluded in our analysis)

reason4exclusion (reason why this SNP was excluded)

phenotype (phenotyp setting)