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Structure of the p53 cancer mutant Y220C with bound small-molecule stabilizer PhiKan5149

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Protein Data Bank Japan2024-01-10 更新2026-03-21 收录
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Structure of the p53 cancer mutant Y220C with bound small-molecule stabilizer PhiKan5149 Descriptor: 1-{1-[(3-bromo-5-chloro-2-hydroxyphenyl)methyl piperidin-4-yl}piperidin-4-ol], CELLULAR TUMOR ANTIGEN P53, ZINC ION Authors: Joerger, A.C. Deposit date: 2015-08-04 Release date: 2015-12-16 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53. Structure, 23, 2015

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2015-08-04
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