Characterization of liver immune cell subsets of primary biliary cholangitis (PBC) mouse models using single-cell RNA sequencing
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https://www.ncbi.nlm.nih.gov/sra/SRP342563
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资源简介:
We characterized difference immune cell subsets in liver microenvironment between PBC mouse models (mainly dnTGFÃRII mice) and wild type mouse by transcriptome and proteome single cell squencing, and discovered an unconventional cytotoxic CD8aa T cells increased in dnTGFÃRII mice. Overall design: CD45+ immune cells sorted from liver of wild type mice and PBC mouse models, including dnTGFÃRII mice, IFN-? ARE-Del-/- mice and P40-/-IL-2Ra-/- mice.
创建时间:
2022-05-12



