Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease characterized by a late clinical onset of psychiatric, cognitive, and motor symptoms. Transcriptional dysregulation is an e
5 mice per group of each: R6/2 and isogenic wild-type controls. Overall design: Total RNA was isolated and sequenced from the striatum of R6/2 HD model and Control mice (11 weeks of age).
This is a longitudinal project in resting-state fMRI across different ages of the zQ175DN HET mouse model of Huntington's disease and age-matched controls. This data set has been used in the following