Animal models of Staphylococcus aureus infective endocarditis (IE), especially in rodents, are commonly used to investigate the underlying pathogenesis, disease progression, potential diagnostic appro

NIAID Data Ecosystem20

Therapeutic Efficacy of GAR-936, a Novel Glycylcycline, in a Rat Model of Experimental Endocarditis

抗菌药物体内药效评估

感染性心内膜炎动物模型

GAR-936, a novel glycylcycline, was investigated with a rat model of experimental endocarditis. It was compared with vancomycin against both vancomycin-susceptible and -resistant Enterococcus faecalis

PubMed Central00

Table_1_Isolating Crucial Steps in Induction of Infective Endocarditis With Preclinical Modeling of Host Pathogen Interaction.docx

感染性心内膜炎动物模型

宿主-病原体相互作用

NIAID Data Ecosystem30

Single-Oral-Dose Azithromycin Prophylaxis against Experimental Streptococcal or Staphylococcal Aortic Valve Endocarditis

感染性心内膜炎动物模型

抗生素疗效评估

Azithromycin and ampicillin protected 94 and 72% of animals challenged with Streptococcus oralis, respectively (P = 0.177), while azithromycin and vancomycin protected 59 and 94% of the methicillin-re

PubMed Central00

Single strain infection model of endocarditis in rats, 72 h post-infection.

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