Human GAR transformylase in complex with GAR and pemetrexed

Human GAR transformylase in complex with GAR and pemetrexed Descriptor: GLYCINAMIDE RIBONUCLEOTIDE, N-{4-[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid, Trifunctional purine biosynthetic protein adenosine-3 Authors: Deis, S.M, Dann III, C.E. Deposit date: 2015-05-22 Release date: 2015-12-16 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.504 Å) Cite: 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors. J.Med.Chem., 58, 2015