官方服务：
资源简介：
MST2 kinase assay
应用场景：
创建时间：
2020-10-20
相关数据集
Quantitative Interpretation of Intracellular Drug Binding and Kinetics Using the Cellular Thermal Shift Assay
Evidence of physical interaction with the target protein is essential in the development of chemical probes and drugs. The cellular thermal shift assay (CETSA) allows evaluation of drug binding in liv
NIAID Data Ecosystem110
KINATEST-ID: A Pipeline To Develop Phosphorylation-Dependent Terbium Sensitizing Kinase Assays
Nonreceptor protein tyrosine kinases (NRTKs) are essential for cellular homeostasis and thus are a major focus of current drug discovery efforts. Peptide substrates that can enhance lanthanide ion lum
NIAID Data Ecosystem60
Comparative Study of Allosteric GPCR Binding Sites and Their Ligandability Potential
The steadily growing number of experimental G-protein-coupled receptor (GPCR) structures has revealed diverse locations of allosteric modulation, and yet few drugs target them. This gap highlights the
Figshare2024-10-23 更新40
A preclinical candidate of cyclophilin D inhibition improves alcohol-associated liver injury
Currently, no therapies are approved for alcohol-associated liver disease (ALD). Here, we identify cyclophilin D (CypD) as a critical mediator in the progression of ALD. We observe elevated expression
NIAID Data Ecosystem110
AMPK inhibitors may be potential drugs for STING-induced inflammatory diseases.
AMPK inhibitors suppress inflammatory gene expression induced by STING R284S variants. STING R284S variant was expressed in STING-/- MEF cells. RNA was extracted from the MEF cells after treated with
NIAID Data Ecosystem40
