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The First Single-Cell Sequencing of Plasmodiophora brassicae Reveals Genetic Diversity and Clonal Dynamics

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NIAID Data Ecosystem2026-05-02 收录
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A method was developed to enzymatically remove cell walls from dormant spores of Plasmodiophora brassicae, enabling the first single-cell sequencing of this clubroot pathogen, revealing high genetic diversity among ~4000 protoplasts. The predominance of distinct genotypes suggests clonal reproduction, complicating single-gene resistance management in brassica crops.

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2025-05-14
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