Candidate models of eQTN locations, ranked by AIC.

The table compares the performance of seven different hierarchical models of eQTN locations. In each model we used either a single “anchor” point to predict the locations of eQTNs (e.g., the location of the TSS) or two anchor points (e.g., the TSS and TES locations). The “TSS+CDSE” model uses the TSS and the coding sequence end locations as anchors; similarly “probe” refers to the location of the probe and “TXMID” is the midpoint of the transcript. The second and third columns compare the model listed on that line against the best model (TSS+TES), in terms of the difference in log likelihood (column 2) and the difference in Akaike Information Criterion (AIC, column 3). AIC penalizes the two-anchor models for 51 additional parameters compared to the one-anchor models.