Lepidodactylus lugubris strain:not applicable | isolate:MG-2025 | cultivar:not applicable Genome sequencing
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP605946
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Lizards are the only amniote group that includes obligate parthenogenetic species capable of blastema-based appendage regeneration. These clonally-reproducing species make attractive research models because they allow for allogeneic cell transplantations without immune reactivity. Of these parthenogenetic lizards, the "Type A" population of the mourning gecko (Lepidodactylus lugubris) is distinguished by ready availability, ease of care, high productivity, and a diploid genome, which facilitates gene editing methods such as CRISPR/Cas9. These features make L. lugubris particularly suited as a model for studying the genetic, molecular, and cellular mechanisms underlying fibrosis suppression and tissue regeneration. We report a contiguous genome of L. lugubris with a total size of 3.52 Gb, a total of 9,240 scaffolds, L50 of 15 bp, and N50 of 92.462 Mb. Repetitive content consists of 47.71% of the genome, and a total of 34,992 genes were annotated. Assembly of the mourning gecko genome provides a valuable resource for studying the transcriptomic and epigenetic changes that lizard cells undergo during blastema formation and appendage regrowth.
创建时间:
2025-09-02



