Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex

Crystal Structure of the Antithrombin-S195A Factor Xa-Pentasaccharide Complex Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, ... Authors: Johnson, D.J, Li, W, Adams, T.E, Huntington, J.A. Deposit date: 2006-03-15 Release date: 2006-05-09 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activation. Embo J., 25, 2006