Beta cell 5’-shifted isomiRs are candidate regulatory hubs in type 2 diabetes

ChEBI2013-09-10 更新2026-07-21 收录

糖尿病分子机制

isomiR调控网络

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-44262 数据链接链接失效反馈

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资源简介：

Beta cell 5’-shifted isomiRs are candidate regulatory hubs in type 2 diabetes

创建时间：

2013-09-10

RNA-seq of mice islets from wt and miR-29a/b-1 pancreatic beta cell specific overexpression transgenic mice

胰腺β细胞功能研究

糖尿病分子机制

We investigated the mechanism associated with miR-29 effects by comparing gene expression of whole primary islets isolated from miR-29a/b-1 pancreatic beta cell specific overexpression transgenic mice

NIAID Data Ecosystem120

Understanding oxidative stress responses in pancreatic islet cells by single cell RNA-sequencing analysis

单细胞转录组学

糖尿病分子机制

We found these ROS generation is regulated by lncRNA MALAT1 and genetic ablation of MALAT1 drastically reduced ROS level and oxidative stress in mouse islet cells with the benefits of improved insulin

NIAID Data Ecosystem90

RNAseq of L cells from Gcg-Venus HFD-STZ mice

糖尿病分子机制

单细胞转录组学

Determine the role of L cell Scgn in a murine model of type 2 diabetes

NIAID Data Ecosystem40

ADAR1-dependent editing participates to the human beta-cells transcriptome diversity during inflammation

糖尿病分子机制

RNA修饰与免疫调控

Enterovirus infection has long been suspected as a possible trigger for type 1 diabetes. Upon infection, viral double-stranded RNA (dsRNA) is recognized by membrane and cytosolic sensors that orchestr

NIAID Data Ecosystem100

Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients. Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients

糖尿病分子机制

中医智能诊断

In traditional Chinese medicine (TCM), blood stasis syndrome (BSS) is mainly manifested by the increase of blood viscosity, platelet adhesion rate and aggregation, and the change of microcirculation,

NIAID Data Ecosystem80

Beta cell 5’-shifted isomiRs are candidate regulatory hubs in type 2 diabetes

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