A Chinese herbal formula, Gengnianchun, ameliorates ß-amyloid peptide toxicity in a Caenorhabditis elegans model of Alzheimer's disease

To further investigate the transcriptional effects of GNC treatment, we analyzed gene expression of C. elegans wild-type N2 in NGM supplemented with GNC (3.94 mg/mL) and nematodes maintained in control condition at the same age (old worms, 22-days old) using next-generation sequencing (NGS) Overall design: Examination of C. elegans wild-type N2 in NGM supplemented with GNC (3.94 mg/mL) and nematodes maintained in control condition.