Supplemental Figure 7

Supplemental Figure 7. Protection by ultrasound depends on an intact spleen. The protective effects of ultrasound were removed by prior splenectomy A) Study Design. Mice underwent splenectomy one week prior to sham or pUS treatment (Day 0). Twenty-four hours following pUS or sham, mice were injected with Folic Acid (FA). B) Plasma creatinine and C) Plasma BUN at 48h following FA. D) Percent change in body weight (BW) 48 hours after FA (Day 0). E) Kidney weight (right and left) at the time of harvest normalized to body weight of each mouse (Day 0). Data are represented as mean ± SEM. Significance was determined using the unpaired Student’s t test.